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硼替佐米对伊马替尼耐药细胞株K562的凋亡作用及机制

OBJECTIVE: To investigate the effect of bortezomib in inducing apoptosis in imatinib-resistant K562 (K562R) cells and its possible mechanism. METHODS: K562 cells were cultured in gradient concentrations of imatinib for several months to generate imatinib-resistant K562 cells. The viability of K562R...

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Bibliographic Details
Published in:Nan Fang Yi Ke Da Xue Xue Bao
Format: Artigo
Language:Inglês
Published: 南方医科大学学报编辑部 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6765724/
https://ncbi.nlm.nih.gov/pubmed/28801299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3969/j.issn.1673-4254.2017.08.23
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