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雌二醇与ESR1靶向结合通过ERK信号通路调控软骨细胞的增殖

OBJECTIVE: To investigate the effect of estradiol (E2)/estrogen receptor 1 (ESR1) on the proliferation of human chondrocytes in vitro and explore the molecular mechanism. METHODS: The Ad-Easy adenovirus packaging system was used to construct and package the ESR1-overexpressing adenovirus Ad-ESR1. We...

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Bibliografske podrobnosti
izdano v:Nan Fang Yi Ke Da Xue Xue Bao
Format: Artigo
Jezik:Inglês
Izdano: 南方医科大学学报编辑部 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6765635/
https://ncbi.nlm.nih.gov/pubmed/30890499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12122/j.issn.1673-4254.2019.02.02
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