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雷帕霉素通过上调TGF-β/smad信号通路减轻小鼠的实验性自身免疫性脑脊髓炎

OBJECTIVE: To evaluate the efficacy of rapmycin for treatment of experimental autoimmune encephalomyelitis (EAE) in mice and explore the underlying mechanism. METHODS: An EAE model was established in C57BL/6 mice. After immunization, the mice were divided into model group and rapamycin groups treate...

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Bibliografiset tiedot
Julkaisussa:Nan Fang Yi Ke Da Xue Xue Bao
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 南方医科大学学报编辑部 2019
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6765580/
https://ncbi.nlm.nih.gov/pubmed/30692064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12122/j.issn.1673-4254.2019.01.06
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