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siRNA介导的PD-L1沉默可增强人CD8(+)T淋巴细胞的体外杀伤作用
OBJECTIVE: To investigate the effect of small interfering RNA (siRNA)-mediated silencing of programmed cell deathligand 1 (PD-L1) in human glioma cells on the cytotoxicity of human CD8(+)T lymphocytes against the modified tumor cells. METHODS: A siRNA sequence targeting PD-L1 gene was designed and t...
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| Publicado no: | Nan Fang Yi Ke Da Xue Xue Bao |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
南方医科大学学报编辑部
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6765535/ https://ncbi.nlm.nih.gov/pubmed/33168513 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3969/j.issn.1673-4254.2018.07.05 |
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