Llwytho...

Immunogenicity of a rheumatoid arthritis protective sequence when acquired through microchimerism

HLA class II genes provide the strongest genetic contribution to rheumatoid arthritis (RA). HLA-DRB1 alleles encoding the sequence DERAA are RA-protective. Paradoxically, RA risk is increased in women with DERAA(+) children born prior to onset. We developed a sensitive qPCR assay specific for DERAA,...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Proc Natl Acad Sci U S A
Prif Awduron: Kanaan, Sami B., Sensoy, Oyku, Yan, Zhen, Gadi, Vijayakrishna K., Richardson, Michael L., Nelson, J. Lee
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2019
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6765309/
https://ncbi.nlm.nih.gov/pubmed/31501349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1904779116
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