Targeted mobilization of Lrig1(+) gastric epithelial stem cell populations by a carcinogenic Helicobacter pylori type IV secretion system

Helicobacter pylori-induced gastritis is the strongest risk factor for gastric adenocarcinoma, a malignancy preceded by a series of well-defined histological stages, including metaplasia. One microbial constituent that augments cancer risk is the cag type 4 secretion system (T4SS), which translocate...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Wroblewski, Lydia E., Choi, Eunyoung, Petersen, Christine, Delgado, Alberto G., Piazuelo, M. Blanca, Romero-Gallo, Judith, Lantz, Tyler L., Zavros, Yana, Coffey, Robert J., Goldenring, James R., Zemper, Anne E., Peek, Richard M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2019
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6765285/
https://ncbi.nlm.nih.gov/pubmed/31488717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1903798116
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