The mRNA degradation factor Xrn1 regulates transcription elongation in parallel to Ccr4

Co-transcriptional imprinting of mRNA by Rpb4 and Rpb7 subunits of RNA polymerase II (RNAPII) and by the Ccr4–Not complex conditions its post-transcriptional fate. In turn, mRNA degradation factors like Xrn1 are able to influence RNAPII-dependent transcription, making a feedback loop that contribute...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Begley, Victoria, Corzo, Daniel, Jordán-Pla, Antonio, Cuevas-Bermúdez, Abel, de Miguel-Jiménez, Lola, Pérez-Aguado, David, Machuca-Ostos, Mercedes, Navarro, Francisco, Chávez, María José, Pérez-Ortín, José E, Chávez, Sebastián
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Gene regulation, Chromatin and Epigenetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6765136/
https://ncbi.nlm.nih.gov/pubmed/31392315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz660
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