Obstructive sleep apnea and longitudinal Alzheimer’s disease biomarker changes

STUDY OBJECTIVES: To determine the effect of self-reported clinical diagnosis of obstructive sleep apnea (OSA) on longitudinal changes in brain amyloid PET and CSF biomarkers (Aβ42, T-tau, and P-tau) in cognitively normal (NL), mild cognitive impairment (MCI), and Alzheimer’s disease (AD) elderly. M...

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Udgivet i:Sleep
Main Authors: Bubu, Omonigho M, Pirraglia, Elizabeth, Andrade, Andreia G, Sharma, Ram A, Gimenez-Badia, Sandra, Umasabor-Bubu, Ogie Q, Hogan, Megan M, Shim, Amanda M, Mukhtar, Fahad, Sharma, Nidhi, Mbah, Alfred K, Seixas, Azizi A, Kam, Korey, Zizi, Ferdinand, Borenstein, Amy R, Mortimer, James A, Kip, Kevin E, Morgan, David, Rosenzweig, Ivana, Ayappa, Indu, Rapoport, David M, Jean-Louis, Girardin, Varga, Andrew W, Osorio, Ricardo S
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2019
Fag:
Neurological Disorders
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6765111/
https://ncbi.nlm.nih.gov/pubmed/30794315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/sleep/zsz048
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