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A randomized, placebo- and active-controlled, multi-country, multi-center parallel group trial to evaluate the efficacy and safety of a fixed-dose combination of 400 mg ibuprofen and 100 mg caffeine compared with ibuprofen 400 mg and placebo in patients with acute lower back or neck pain

BACKGROUND: Ibuprofen is a well-established analgesic for acute pain symptoms. In several acute pain models, caffeine has demonstrated an analgesic adjuvant effect. This randomized trial (NCT03003000) was designed to compare the efficacy of a fixed-dose combination of ibuprofen and caffeine with ibu...

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Bibliografske podrobnosti
izdano v:J Pain Res
Main Authors: Predel, Hans-Georg, Ebel-Bitoun, Caty, Lange, Robert, Weiser, Thomas
Format: Artigo
Jezik:Inglês
Izdano: Dove 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6765100/
https://ncbi.nlm.nih.gov/pubmed/31576162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/JPR.S217045
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