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Tissue-engineered blood-brain barrier models via directed differentiation of human induced pluripotent stem cells
Three-dimensional (3D) tissue-engineered models of the blood-brain barrier (BBB) recapitulate in vivo shear stress, cylindrical geometry, and cell-ECM interactions. Here we address four issues associated with BBB models: cell source, barrier function, cryopreservation, and matrix stiffness. We repro...
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| Veröffentlicht in: | Sci Rep |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group UK
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6764995/ https://ncbi.nlm.nih.gov/pubmed/31562392 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-50193-1 |
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