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A Machine Learning Classifier for Assigning Individual Patients with Systemic Sclerosis to Intrinsic Molecular Subsets

OBJECTIVE: High-throughput gene expression profiling of tissue samples from patients with systemic sclerosis (SSc) has identified four “intrinsic” gene expression subsets: inflammatory, fibroproliferative, normal-like, and limited. Prior methods required agglomerative clustering of many samples. In...

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Detalhes bibliográficos
Publicado no:Arthritis Rheumatol
Main Authors: Franks, Jennifer M., Martyanov, Viktor, Cai, Guoshuai, Wang, Yue, Li, Zhenghui, Wood, Tammara A., Whitfield, Michael L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6764877/
https://ncbi.nlm.nih.gov/pubmed/30920766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.40898
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