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PARP-1 and its associated nucleases in DNA damage response
Poly(ADP-ribose) (PAR) polymerase-1 (PARP-1) acts as a DNA damage sensor. It recognizes DNA damage and facilitates DNA repair by recruiting DNA repair machinery to damage sites. Recent studies reported that PARP-1 also plays an important role in DNA replication by recognizing the unligated Okazaki f...
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| Publicado no: | DNA Repair (Amst) |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6764844/ https://ncbi.nlm.nih.gov/pubmed/31302005 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2019.102651 |
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