Diverse EGFR Exon 20 Insertions and Co-Occurring Molecular Alterations Identified by Comprehensive Genomic Profiling of Non-Small Cell Lung Cancer

INTRODUCTION: EGFR exon 20 insertions (EGFRex20ins) comprise an uncommon subset of EGFR activating alterations relatively insensitive to first and second-generation EGFR tyrosine kinase inhibitors (TKIs). However, recent early clinical data suggests these patients may benefit from newer generation E...

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Publicat a:J Thorac Oncol
Autors principals: Riess, Jonathan W., Gandara, David R., Frampton, Garrett M., Madison, Russell, Peled, Nir, Bufill, Jose A., Dy, Grace, Ou, Sai-Hong Ignatius, Stephens, Philip J., McPherson, John, Lara, Primo N., Burich, Rebekah A., Ross, Jeffrey S., Miller, Vincent A., Ali, Siraj M., Mack, Philip C., Schrock, Alexa B.
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6764748/
https://ncbi.nlm.nih.gov/pubmed/29981927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtho.2018.06.019
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