Confounding by indication of the safety of de-escalation in community-acquired pneumonia: A simulation study embedded in a prospective cohort

Observational studies have demonstrated that de-escalation of antimicrobial therapy is independently associated with lower mortality. This most probably results from confounding by indication. Reaching clinical stability is associated with the decision to de-escalate and with survival. However, stud...

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Enregistré dans:
Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: van Heijl, Inger, Schweitzer, Valentijn A., Boel, C. H. Edwin, Oosterheert, Jan Jelrik, Huijts, Susanne M., Dorigo-Zetsma, Wendelien, van der Linden, Paul D., Bonten, Marc J. M., van Werkhoven, Cornelis H.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2019
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6764693/
https://ncbi.nlm.nih.gov/pubmed/31560686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0218062
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