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Raising the Bar On-Bead: Efficient On-Resin Synthesis of α-Conotoxin LvIA
α4/7-Conotoxin LvIA is an isoform-selective inhibitor of the α3β2 nicotinic acetylcholine receptor. An efficient strategy for the synthesis of this toxin is critical to advancing its utility as a probe for receptor function and as a potential pharmaceutical lead target. On-resin methods for peptide...
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| Veröffentlicht in: | Tetrahedron Lett |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6764457/ https://ncbi.nlm.nih.gov/pubmed/31564757 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2018.11.048 |
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