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Comparison of extended to standard half-life recombinant factor VIII therapy in patients with hemophilia A on prophylactic therapy

Background: Hemophilia A is a genetic bleeding disorder caused by a deficiency in factor VIII (FVIII). FVIII maintains bleeding homeostasis within the body through its downstream effects on the intrinsic clotting cascade. The extent of the disease – mild, moderate or severe – depends on the amount o...

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Pubblicato in:J Drug Assess
Autori principali: McCall, Michael, Koerner, Pamela, Miller, Rick, Radi, Melanie
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6764360/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21556660.2019.1658327
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