Butyrate Does Not Protect Against Inflammation-induced Loss of Epithelial Barrier Function and Cytokine Production in Primary Cell Monolayers From Patients With Ulcerative Colitis

BACKGROUND AND AIMS: In vitro studies using immortalised cancer cell lines showed that butyrate has an overall positive effect on epithelial barrier integrity, but the physiological relevance of cancer cell lines is limited. We developed epithelial monolayers from human tissue samples of patients wi...

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Detalhes bibliográficos
Publicado no:J Crohns Colitis
Main Authors: Vancamelbeke, Maaike, Laeremans, Thessa, Vanhove, Wiebe, Arnauts, Kaline, Ramalho, Anabela Santo, Farré, Ricard, Cleynen, Isabelle, Ferrante, Marc, Vermeire, Séverine
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6764103/
https://ncbi.nlm.nih.gov/pubmed/30919886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ecco-jcc/jjz064
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