Effect of 1 or 2 Doses of Inclisiran on Low-Density Lipoprotein Cholesterol Levels: One-Year Follow-up of the ORION-1 Randomized Clinical Trial

IMPORTANCE: Sustained reductions in low-density lipoprotein cholesterol (LDL-C) with lipid-lowering therapies that require frequent dosing are reliant on patient adherence, and poor adherence is associated with worse clinical outcomes. OBJECTIVE: To determine whether inclisiran, a small interfering...

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Detalhes bibliográficos
Publicado no:JAMA Cardiol
Main Authors: Ray, Kausik K., Stoekenbroek, Robert M., Kallend, David, Nishikido, Toshiyuki, Leiter, Lawrence A., Landmesser, Ulf, Wright, R. Scott, Wijngaard, Peter L. J., Kastelein, John J. P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Medical Association 2019
Assuntos:
Original Investigation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6763983/
https://ncbi.nlm.nih.gov/pubmed/31553410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamacardio.2019.3502
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