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Gene Therapy for Methylmalonic Acidemia: Past, Present, and Future

Methylmalonic acidemia (MMA) is a severe, and sometimes lethal, monogenic metabolic disorder in need of improved treatments. A number of new genomic therapies, which include canonical adeno-associated virus gene addition, genome editing, and systemic mRNA therapy, have shown great promise in murine...

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Detalhes bibliográficos
Publicado no:Hum Gene Ther
Main Authors: Chandler, Randy J., Venditti, Charles P.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc., publishers 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6763959/
https://ncbi.nlm.nih.gov/pubmed/31303064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2019.113
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