GABA(B2) Is Essential for G-Protein Coupling of the GABA(B) Receptor Heterodimer

GABA(B) receptors are unique among G-protein-coupled receptors (GPCRs) in their requirement for heterodimerization between two homologous subunits, GABA(B1)and GABA(B2), for functional expression. Whereas GABA(B1) is capable of binding receptor agonists and antagonists, the role of each GABA(B) subu...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Robbins, Melanie J., Calver, Andrew R., Filippov, Alexander K., Hirst, Warren D., Russell, Robert B., Wood, Martyn D., Nasir, Shabina, Couve, Andrés, Brown, David A., Moss, Stephen J., Pangalos, Menelas N.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2001
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ARTICLE
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6763845/
https://ncbi.nlm.nih.gov/pubmed/11588177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.21-20-08043.2001
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