Diagnosis of Idiopathic GHD in Children Based on Response to rhGH Treatment: The Importance of GH Provocative Tests and IGF-1

Purpose: Serum IGF-1 (Insulin like growth factor 1) and Growth Hormone (GH) provocative tests are reasonable tools for screening and diagnosis of idiopathic GH Deficiency (IGHD). However, the average cut-off points applied on these tests have a lower level of evidence and produce large amounts of fa...

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Vydáno v:Front Endocrinol (Lausanne)
Hlavní autoři: Felício, João Soares, Janaú, Luísa Corrêa, Moraes, Marcelle Alves, Zahalan, Nathalie Abdallah, de Souza Resende, Fabrício, de Lemos, Manuela Nascimento, de Souza Neto, Norberto Jorge Kzan, Farias de Franco, Isabela Imbelloni, Leitão, Loyane Tamyres Costa, Silva, Lilian de Souza d'Albuquerque, de Oliveira, Maria Clara Neres Iunes, de Alcântara, Angélica Leite, Contente Braga de Souza, Ana Carolina, da Silva, Wanderson Maia, dos Santos, Márcia Costa, de Queiroz, Natércia Neves Marques, de Moraes, Lorena Vilhena, de Figueiredo, Antônio Bentes, Farinassi, Ana Luiza Prieto, Farias, Luciana Marques da Costa, da Silva, Danielle Dias, Felício, Karem Miléo, Abrahão Neto, João Felício
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2019
Témata:
Endocrinology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6763693/
https://ncbi.nlm.nih.gov/pubmed/31616374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2019.00638
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