Morin Hydrate Inhibits TREM-1/TLR4-Mediated Inflammatory Response in Macrophages and Protects Against Carbon Tetrachloride-Induced Acute Liver Injury in Mice

This study aims to investigate the protective effects of morin hydrate (MH) against acute liver injury induced by carbon tetrachloride (CCl(4)) in mice and to elucidate the possible molecular mechanism of action. Mice were pretreated with MH (50 mg/kg body weight) or vehicle by oral gavage once dail...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Front Pharmacol
Main Authors: Li, Xi, Yao, Qunyan, Huang, Jiying, Jin, Qianwen, Xu, Beili, Chen, Fangyuan, Tu, Chuantao
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2019
Teme:
Pharmacology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6763683/
https://ncbi.nlm.nih.gov/pubmed/31616301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.01089
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