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Switching From a Protease Inhibitor–based Regimen to a Dolutegravir-based Regimen: A Randomized Clinical Trial to Determine the Effect on Peripheral Blood and Ileum Biopsies From Antiretroviral Therapy–suppressed Human Immunodeficiency Virus–infected Individuals

BACKGROUND: Optimization of combination antiretroviral therapy (cART) can impact the human immunodeficiency virus (HIV) reservoir. We evaluated the effect on the HIV reservoir in peripheral blood and ileum biopsies in patients switching from boosted protease inhibitor (PI/r)–based therapy to doluteg...

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Detalhes bibliográficos
Publicado no:Clin Infect Dis
Main Authors: Morón-López, Sara, Navarro, Jordi, Jimenez, Montse, Rutsaert, Sofie, Urrea, Víctor, Puertas, Maria C, Torrella, Ariadna, De Clercq, Laura, Ribas, Bibiana Planas, Gálvez, Cristina, Salgado, Maria, Vandekerckhove, Linos, Blanco, Julià, Crespo, Manel, Martinez-Picado, Javier
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6763634/
https://ncbi.nlm.nih.gov/pubmed/30590412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cid/ciy1095
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