Flotillins promote T cell receptor sorting through a fast Rab5–Rab11 endocytic recycling axis

The targeted endocytic recycling of the T cell receptor (TCR) to the immunological synapse is essential for T cell activation. Despite this, the mechanisms that underlie the sorting of internalised receptors into recycling endosomes remain poorly understood. To build a comprehensive picture of TCR r...

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Publicat a:Nat Commun
Autors principals: Redpath, Gregory M. I., Ecker, Manuela, Kapoor-Kaushik, Natasha, Vartoukian, Haig, Carnell, Michael, Kempe, Daryan, Biro, Maté, Ariotti, Nicholas, Rossy, Jérémie
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6763463/
https://ncbi.nlm.nih.gov/pubmed/31558725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-12352-w
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