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Novel RNA-targeted therapies for hereditary ATTR amyloidosis and their impact on the autonomic nervous system

PURPOSE: Transthyretin-mediated hereditary amyloidosis (hATTR amyloidosis) is a multisystemic disease with heterogeneous clinical presentation. Hallmarks of the disease are sensory-motor and autonomic neuropathy and cardiomyopathy. Two disease-modifying drugs, inotersen (an antisense oligonucleotide...

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Vydáno v:Clin Auton Res
Hlavní autor: Conceição, Isabel
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer Berlin Heidelberg 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6763402/
https://ncbi.nlm.nih.gov/pubmed/31399774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10286-019-00626-8
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