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The Design Principles of Biochemical Timers: Circuits That Discriminate Between Transient and Sustained Stimulation

Many cellular responses for which timing is critical display temporal filtering – the ability to suppress response until stimulated for longer than a given minimal time. To identify biochemical circuits capable of kinetic filtering, we comprehensively searched the space of three-node enzymatic netwo...

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Pubblicato in:Cell Syst
Autori principali: Gerardin, Jaline, Reddy, Nishith R., Lim, Wendell A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6763348/
https://ncbi.nlm.nih.gov/pubmed/31521602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cels.2019.07.008
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