Synthetic self-assembling ADDomer platform for highly efficient vaccination by genetically encoded multiepitope display

Self-assembling virus-like particles represent highly attractive tools for developing next-generation vaccines and protein therapeutics. We created ADDomer, an adenovirus-derived multimeric protein-based self-assembling nanoparticle scaffold engineered to facilitate plug-and-play display of multiple...

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Foilsithe in:Sci Adv
Main Authors: Vragniau, Charles, Bufton, Joshua C., Garzoni, Frédéric, Stermann, Emilie, Rabi, Fruzsina, Terrat, Céline, Guidetti, Mélanie, Josserand, Véronique, Williams, Matt, Woods, Christopher J., Viedma, Gerardo, Bates, Phil, Verrier, Bernard, Chaperot, Laurence, Schaffitzel, Christiane, Berger, Imre, Fender, Pascal
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Association for the Advancement of Science 2019
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Research Articles
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6763337/
https://ncbi.nlm.nih.gov/pubmed/31620562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aaw2853
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