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Mast cell peptidases (carboxypeptidase A and chymase)-mediated hydrolysis of human angiotensin-(1–12) substrate

Angiotensin processing peptidases (carboxypeptidase A (CPA) and chymase) are stored in cardiac mast cell (MC) secretory granules in large quantity and are co-released into the extracellular environment after activation/degranulation. In the human heart, chymase is primarily responsible for angiotens...

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Detalhes bibliográficos
Publicado no:Biochem Biophys Res Commun
Main Authors: Ahmad, Sarfaraz, Wright, Kendra N., Sun, Xuming, Groban, Leanne, Ferrario, Carlos M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6763271/
https://ncbi.nlm.nih.gov/pubmed/31466718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2019.08.098
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