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Mucosal CD8+ T cell responses induced by an MCMV based vaccine vector confer protection against influenza challenge

Cytomegalovirus (CMV) is a ubiquitous β-herpesvirus that establishes life-long latent infection in a high percentage of the population worldwide. CMV induces the strongest and most durable CD8(+) T cell response known in human clinical medicine. Due to its unique properties, the virus represents a p...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Zheng, Xiaoyan, Oduro, Jennifer D., Boehme, Julia D., Borkner, Lisa, Ebensen, Thomas, Heise, Ulrike, Gereke, Marcus, Pils, Marina C., Krmpotic, Astrid, Guzmán, Carlos A., Bruder, Dunja, Čičin-Šain, Luka
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6763260/
https://ncbi.nlm.nih.gov/pubmed/31525249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008036
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