Enhancing glycolysis attenuates Parkinson’s disease progression in models and clinical databases

Parkinson’s disease (PD) is a common neurodegenerative disease that lacks therapies to prevent progressive neurodegeneration. Impaired energy metabolism and reduced ATP levels are common features of PD. Previous studies revealed that terazosin (TZ) enhances the activity of phosphoglycerate kinase 1...

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Publicado en:J Clin Invest
Autores principales: Cai, Rong, Zhang, Yu, Simmering, Jacob E., Schultz, Jordan L., Li, Yuhong, Fernandez-Carasa, Irene, Consiglio, Antonella, Raya, Angel, Polgreen, Philip M., Narayanan, Nandakumar S., Yuan, Yanpeng, Chen, Zhiguo, Su, Wenting, Han, Yanping, Zhao, Chunyue, Gao, Lifang, Ji, Xunming, Welsh, Michael J., Liu, Lei
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 2019
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6763248/
https://ncbi.nlm.nih.gov/pubmed/31524631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI129987
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