Potential role of iron in repair of inflammatory demyelinating lesions

Inflammatory destruction of iron-rich myelin is characteristic of multiple sclerosis (MS). Although iron is needed for oligodendrocytes to produce myelin during development, its deposition has also been linked to neurodegeneration and inflammation, including in MS. We report perivascular iron deposi...

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Detalles Bibliográficos
Publicado en:J Clin Invest
Autores principales: Lee, Nathanael J., Ha, Seung-Kwon, Sati, Pascal, Absinta, Martina, Nair, Govind, Luciano, Nicholas J., Leibovitch, Emily C., Yen, Cecil C., Rouault, Tracey A., Silva, Afonso C., Jacobson, Steven, Reich, Daniel S.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 2019
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6763243/
https://ncbi.nlm.nih.gov/pubmed/31498148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI126809
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