Potential role of iron in repair of inflammatory demyelinating lesions

Inflammatory destruction of iron-rich myelin is characteristic of multiple sclerosis (MS). Although iron is needed for oligodendrocytes to produce myelin during development, its deposition has also been linked to neurodegeneration and inflammation, including in MS. We report perivascular iron deposi...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Lee, Nathanael J., Ha, Seung-Kwon, Sati, Pascal, Absinta, Martina, Nair, Govind, Luciano, Nicholas J., Leibovitch, Emily C., Yen, Cecil C., Rouault, Tracey A., Silva, Afonso C., Jacobson, Steven, Reich, Daniel S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6763243/
https://ncbi.nlm.nih.gov/pubmed/31498148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI126809
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