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Potential role of iron in repair of inflammatory demyelinating lesions

Inflammatory destruction of iron-rich myelin is characteristic of multiple sclerosis (MS). Although iron is needed for oligodendrocytes to produce myelin during development, its deposition has also been linked to neurodegeneration and inflammation, including in MS. We report perivascular iron deposi...

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Veröffentlicht in:J Clin Invest
Hauptverfasser: Lee, Nathanael J., Ha, Seung-Kwon, Sati, Pascal, Absinta, Martina, Nair, Govind, Luciano, Nicholas J., Leibovitch, Emily C., Yen, Cecil C., Rouault, Tracey A., Silva, Afonso C., Jacobson, Steven, Reich, Daniel S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2019
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6763243/
https://ncbi.nlm.nih.gov/pubmed/31498148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI126809
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