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Energy Decomposition Analyses Reveal the Origins of Catalyst and Nucleophile Effects on Regioselectivity in Nucleopalladation of Alkenes

Nucleopalladation is one of the most common mechanisms for Pd-catalyzed hydro- and oxidative functionalization of alkenes. Due to the electronic bias of the π-alkene-palladium complexes, nucleopalladations with terminal aliphatic alkenes typically deliver the nucleophile to the more substituted sp(2...

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Publié dans:J Am Chem Soc
Auteurs principaux: Qi, Xiaotian, Kohler, Daniel G., Hull, Kami L., Liu, Peng
Format: Artigo
Langue:Inglês
Publié: 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6763206/
https://ncbi.nlm.nih.gov/pubmed/31322875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.9b02893
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