Mutations in the Caenorhabditis elegans Serotonin Reuptake Transporter MOD-5 Reveal Serotonin-Dependent and -Independent Activities of Fluoxetine

We isolated two mutants defective in the uptake of exogenous serotonin (5-HT) into the neurosecretory motor neurons ofCaenorhabditis elegans. These mutants were hypersensitive to exogenous 5-HT and hyper-responsive in the experience-dependent enhanced slowing response to food modulated by 5-HT. The...

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Detaylı Bibliyografya
Yayımlandı:J Neurosci
Asıl Yazarlar: Ranganathan, Rajesh, Sawin, Elizabeth R., Trent, Carol, Horvitz, H. Robert
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Society for Neuroscience 2001
Konular:
ARTICLE
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6763176/
https://ncbi.nlm.nih.gov/pubmed/11487610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.21-16-05871.2001
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