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Volume-Activated Chloride Currents Contribute to the Resting Conductance and Invasive Migration of Human Glioma Cells
We used an in vitro model for glioma cell invasion (transwell migration assay) and patch-clamp techniques to investigate the role of volume-activated Cl(−) currents (I(Cl,Vol)) in glioma cell invasion. Hypotonic solutions (≈230 mOsm) activated outwardly rectifying currents that reversed near the equ...
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| Pubblicato in: | J Neurosci |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Society for Neuroscience
2001
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6762888/ https://ncbi.nlm.nih.gov/pubmed/11567057 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.21-19-07674.2001 |
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