Inhibition of Mitochondrial Complex II Induces a Long-Term Potentiation of NMDA-Mediated Synaptic Excitation in the Striatum Requiring Endogenous Dopamine

Abnormal involuntary movements and cognitive impairment represent the classical clinical symptoms of Huntington's disease (HD). This genetic disorder involves degeneration of striatal spiny neurons, but not striatal large cholinergic interneurons, and corresponds to a marked decrease in the act...

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Bibliographic Details
Published in:J Neurosci
Main Authors: Calabresi, Paolo, Gubellini, Paolo, Picconi, Barbara, Centonze, Diego, Pisani, Antonio, Bonsi, Paola, Greengard, Paul, Hipskind, Robert A., Borrelli, Emiliana, Bernardi, Giorgio
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 2001
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6762835/
https://ncbi.nlm.nih.gov/pubmed/11438586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.21-14-05110.2001
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