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Kir4.1 Potassium Channel Subunit Is Crucial for Oligodendrocyte Development and In Vivo Myelination

To understand the cellular and in vivo functions of specific K(+) channels in glia, we have studied mice with a null mutation in the weakly inwardly rectifying K(+) channel subunit Kir4.1. Kir4.1−/− mice display marked motor impairment, and the cellular basis is hypomyelination in the spinal cord, a...

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Publicat a:J Neurosci
Autors principals: Neusch, Clemens, Rozengurt, Nora, Jacobs, Russell E., Lester, Henry A., Kofuji, Paulo
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2001
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6762664/
https://ncbi.nlm.nih.gov/pubmed/11466414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.21-15-05429.2001
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