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Identification of Amino Acid Residues in GluR1 Responsible for Ligand Binding and Desensitization
Although GluR1(o) and GluR3(o) are homologous at the amino acid level, GluR3(o) desensitizes approximately threefold faster than GluR1(o). By creating chimeras of GluR1(o) and GluR3(o) and point amino acid exchanges in their S2 regions, two residues were identified to be critical for GluR1(o) desens...
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出版年: | J Neurosci |
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主要な著者: | , , , , , , |
フォーマット: | Artigo |
言語: | Inglês |
出版事項: |
Society for Neuroscience
2001
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主題: | |
オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6762546/ https://ncbi.nlm.nih.gov/pubmed/11312290 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.21-09-03052.2001 |
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