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Identification of Amino Acid Residues in GluR1 Responsible for Ligand Binding and Desensitization

Although GluR1(o) and GluR3(o) are homologous at the amino acid level, GluR3(o) desensitizes approximately threefold faster than GluR1(o). By creating chimeras of GluR1(o) and GluR3(o) and point amino acid exchanges in their S2 regions, two residues were identified to be critical for GluR1(o) desens...

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書誌詳細
出版年:J Neurosci
主要な著者: Banke, T. G., Greenwood, J. R., Christensen, J. K., Liljefors, T., Traynelis, S. F., Schousboe, A., Pickering, Darryl S.
フォーマット: Artigo
言語:Inglês
出版事項: Society for Neuroscience 2001
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6762546/
https://ncbi.nlm.nih.gov/pubmed/11312290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.21-09-03052.2001
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