Functional Analysis of Capsaicin Receptor (Vanilloid Receptor Subtype 1) Multimerization and Agonist Responsiveness Using a Dominant Negative Mutation

The recently cloned vanilloid receptor subtype 1 (VR1) is a ligand-gated channel that is activated by capsaicin, protons, and heat. We have attempted to develop a dominant negative isoform by targeting several mutations of VR1 at highly conserved amino acids or at residues of potential functional im...

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Vydáno v:J Neurosci
Hlavní autoři: Kuzhikandathil, Eldo V., Wang, Haibin, Szabo, Tamas, Morozova, Natasha, Blumberg, Peter M., Oxford, Gerry S.
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2001
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ARTICLE
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6762288/
https://ncbi.nlm.nih.gov/pubmed/11698581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.21-22-08697.2001
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