Progressive Neuronal and Motor Dysfunction in Mice Overexpressing the Serine Protease Inhibitor Protease Nexin-1 in Postmitotic Neurons

Perturbation of the homeostasis between proteases and their inhibitors has been associated with lesion-induced or degenerative neuronal changes. Protease nexin-1 (PN-1), a secreted serine protease inhibitor, is constitutively expressed in distinct neuronal cell populations of the adult CNS. In an ea...

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Publicado no:J Neurosci
Main Authors: Meins, Marita, Piosik, Petra, Schaeren-Wiemers, Nicole, Franzoni, Stefania, Troncoso, Edgardo, Kiss, Jozsef Z., Brösamle, Christian, Schwab, Martin E., Molnár, Zoltán, Monard, Denis
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2001
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ARTICLE
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6762270/
https://ncbi.nlm.nih.gov/pubmed/11698595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.21-22-08830.2001
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