Imputation of canine genotype array data using 365 whole-genome sequences improves power of genome-wide association studies

Genomic resources for the domestic dog have improved with the widespread adoption of a 173k SNP array platform and updated reference genome. SNP arrays of this density are sufficient for detecting genetic associations within breeds but are underpowered for finding associations across multiple breeds...

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Bibliografiska uppgifter
I publikationen:PLoS Genet
Huvudupphovsmän: Hayward, Jessica J., White, Michelle E., Boyle, Michael, Shannon, Laura M., Casal, Margret L., Castelhano, Marta G., Center, Sharon A., Meyers-Wallen, Vicki N., Simpson, Kenneth W., Sutter, Nathan B., Todhunter, Rory J., Boyko, Adam R.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2019
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6762211/
https://ncbi.nlm.nih.gov/pubmed/31525180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1008003
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