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Inhibitions of HMGB1 and TLR4 alleviate DINP-induced asthma in mice

We studied the effects of high mobility group box chromosomal protein 1 (HMGB1) and toll-like receptor (TLR4) in diisonoyl phthalate (DINP)-induced asthma. Mice with DINP-induced asthma were treated with a TLR4-signaling inhibitor or anti-HMGB1 antibody, and various markers of asthma were measured 2...

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Detalhes bibliográficos
Publicado no:Toxicol Res (Camb)
Main Authors: Hwang, Yun-Ho, Lee, Yongjin, Paik, Man-Jeong, Yee, Sung-Tae
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6762012/
https://ncbi.nlm.nih.gov/pubmed/31588340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9tx00048h
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