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Benzisothiazolinone upregulates the MUC5AC expression via ERK1/2, p38, and NF-κB pathways in airway epithelial cells

Mucus plays an important role in protecting the respiratory tract from irritants. However, mucus hypersecretion is a major indicator of airway diseases. 1,2-Benzisothiazolin-3-one (BIT), as a microbicide, induces asthmatic inflammation. Therefore, we focused on the effects of BIT-related mucin secre...

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Detalhes bibliográficos
Publicado no:Toxicol Res (Camb)
Main Authors: Kwak, Soyoung, Choi, Yoon Seok, Na, Hyung Gyun, Bae, Chang Hoon, Song, Si-Youn, Kim, Hyung Geun, Kim, Yong-Dae
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6762011/
https://ncbi.nlm.nih.gov/pubmed/31588347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9tx00135b
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