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DIFFpop: a stochastic computational approach to simulate differentiation hierarchies with single cell barcoding

SUMMARY: DIFFpop is an R package designed to simulate cellular differentiation hierarchies using either exponentially-expanding or fixed population sizes. The software includes functionalities to simulate clonal evolution due to the emergence of driver mutations under the infinite-allele assumption...

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Vydáno v:Bioinformatics
Hlavní autoři: Ferlic, Jeremy, Shi, Jiantao, McDonald, Thomas O, Michor, Franziska
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6761956/
https://ncbi.nlm.nih.gov/pubmed/30816920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btz074
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