DIFFpop: a stochastic computational approach to simulate differentiation hierarchies with single cell barcoding

SUMMARY: DIFFpop is an R package designed to simulate cellular differentiation hierarchies using either exponentially-expanding or fixed population sizes. The software includes functionalities to simulate clonal evolution due to the emergence of driver mutations under the infinite-allele assumption...

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Detaylı Bibliyografya
Yayımlandı:Bioinformatics
Asıl Yazarlar: Ferlic, Jeremy, Shi, Jiantao, McDonald, Thomas O, Michor, Franziska
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2019
Konular:
Applications Notes
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6761956/
https://ncbi.nlm.nih.gov/pubmed/30816920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btz074
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