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A new computational drug repurposing method using established disease–drug pair knowledge

MOTIVATION: Drug repurposing is a potential alternative to the classical drug discovery pipeline. Repurposing involves finding novel indications for already approved drugs. In this work, we present a novel machine learning-based method for drug repurposing. This method explores the anti-similarity b...

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Bibliografiske detaljer
Udgivet i:Bioinformatics
Main Authors: Saberian, Nafiseh, Peyvandipour, Azam, Donato, Michele, Ansari, Sahar, Draghici, Sorin
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6761937/
https://ncbi.nlm.nih.gov/pubmed/30840053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btz156
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