Roles of the Primary Cilium Component Polaris in Synchondrosis Development

Primary cilia regulate several developmental processes and mediate hedgehog signaling. To study their roles in cranial base development, we created conditional mouse mutants deficient in Polaris, a critical primary cilium component, in cartilage. Mutant post-natal cranial bases were deformed, and th...

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Bibliografiske detaljer
Udgivet i:J Dent Res
Main Authors: Ochiai, T., Nagayama, M., Nakamura, T., Morrison, T., Pilchak, D., Kondo, N., Hasegawa, H., Song, B., Serra, R., Pacifici, M., Koyama, E.
Format: Artigo
Sprog:Inglês
Udgivet: SAGE Publications 2009
Fag:
Research Report
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6761730/
https://ncbi.nlm.nih.gov/pubmed/19587160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0022034509337775
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