Divergent neuronal DNA methylation patterns across human cortical development reveal critical periods and a unique role of CpH methylation

BACKGROUND: DNA methylation (DNAm) is a critical regulator of both development and cellular identity and shows unique patterns in neurons. To better characterize maturational changes in DNAm patterns in these cells, we profile the DNAm landscape at single-base resolution across the first two decades...

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Détails bibliographiques
Publié dans:Genome Biol
Auteurs principaux: Price, Amanda J., Collado-Torres, Leonardo, Ivanov, Nikolay A., Xia, Wei, Burke, Emily E., Shin, Joo Heon, Tao, Ran, Ma, Liang, Jia, Yankai, Hyde, Thomas M., Kleinman, Joel E., Weinberger, Daniel R., Jaffe, Andrew E.
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2019
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6761727/
https://ncbi.nlm.nih.gov/pubmed/31554518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-019-1805-1
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