In Vitro Synergy and In Vivo Activity of Tigecycline-Ciprofloxacin Combination Therapy against Vibrio vulnificus Sepsis

The mortality rate associated with Vibrio vulnificus sepsis remains high. An in vitro time-kill assay revealed synergism between tigecycline and ciprofloxacin. The survival rate was significantly higher in mice treated with tigecycline plus ciprofloxacin than in mice treated with cefotaxime plus min...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Kim, Seong Eun, Kim, Hee Kyung, Choi, Su-Mi, Yu, Yohan, Kim, Uh Jin, Darboe, Kalifa Sanneh, Kang, Seung-Ji, Park, Kyung-Hwa, Kang, Gaeun, Kim, Young Ran, Rhee, Joon Haeng, Jung, Sook-In, Jang, Hee-Chang
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
Assuntos:
Experimental Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6761547/
https://ncbi.nlm.nih.gov/pubmed/31332060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00310-19
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