Blockade of Mas Receptor or Mas-Related G-Protein Coupled Receptor Type D Reduces Portal Pressure in Cirrhotic but Not in Non-cirrhotic Portal Hypertensive Rats

Portal hypertension (PHT) resulting from splanchnic vasodilatation is a major cause of morbidity and mortality in patients with cirrhosis. The renin-angiotensin system (RAS) plays an important role in splanchnic vasodilatation in cirrhosis. This study investigated whether acute blockade of the vasod...

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Pubblicato in:Front Physiol
Autori principali: Gunarathne, Lakmie S., Angus, Peter W., Herath, Chandana B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2019
Soggetti:
Physiology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6761391/
https://ncbi.nlm.nih.gov/pubmed/31607942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2019.01169
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